IcsA Is a Shigella flexneri Adhesin Regulated by the Type III Secretion System and Required for Pathogenesis
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منابع مشابه
IcsA is a Shigella flexneri adhesin regulated by the type III secretion system and required for pathogenesis.
Following contact with the epithelium, the enteric intracellular bacterial pathogen Shigella flexneri invades epithelial cells and escapes intracellular phagosomal destruction using its type III secretion system (T3SS). The bacterium replicates within the host cell cytosol and spreads between cells using actin-based motility, which is mediated by the virulence factor IcsA (VirG). Whereas S. fle...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2014
ISSN: 1931-3128
DOI: 10.1016/j.chom.2014.03.001